Method for immunochemical measurement of trace components

Chemistry: analytical and immunological testing – Involving immune complex formed in liquid phase – Separation of immune complex from unbound antigen or antibody

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422 56, 422 57, 430566, 435 4, 435 7, 435805, 436536, 436544, 436805, 436807, G01N 3354, G01N 3352

Patent

active

044042892

ABSTRACT:
In an immunochemical measurement method of an antigen or antibody which comprises competitively reacting an antigen or antibody labelled with spectral sensitizer and an antigen or antibody to be measured, bringing either the reaction product of immune reaction or the unreacted component into contact with silver halide, exposing the same to light having a wavelength which the spectral sensitizer absorbs, developing the exposed silver, and, measuring optical density of the thus formed silver image and/or colored dye, the contact with silver halide is performed in the presence of a specific hydrazine compound. Thus, detection sensitivity is markedly improved.

REFERENCES:
patent: 3782949 (1974-01-01), Olivares
patent: 4331444 (1982-05-01), Mihara
patent: 4337063 (1982-06-01), Mihara
patent: 4337065 (1982-06-01), Hiratsuka

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