Commercial production of avidin in plants

Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or... – The polynucleotide alters fat – fatty oil – ester-type wax – or...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

800DIG56, 800250, 435 691, 4352404, 4353201, 4351723, 435 698, 536235, 536 241, 536 236, C12N 1512, C12N 1529, C12N 1582, A01H 500

Patent

active

057673799

ABSTRACT:
A method for commercial production of avidin entails heterologous expression of the protein in plants, in native conformation, at an expression level such that avidin represents at least 0.1% of total extracted protein. A genetic map of the integration locus allows for the identification of the avidin-expressing plant. Genetic loci on a plant chromosome are revealed that support high levels of avidin expression and that can be used as a site of integration for high level expression of other genes of interest.

REFERENCES:
patent: 4914025 (1990-04-01), Manoil et al.
patent: 4956282 (1990-09-01), Goodman et al.
patent: 5460952 (1995-10-01), Yu et al.
DeLange et al., "Egg White Avidin", Sequence of the 78-Residue Middle Cyanogen Peptide. Complete Amino Acid Sequence of the Protein Subunit, J. of Boil. Chem., vol. 246, No. 3, pp. 698-709, (1971).
Keinanen et al., "Molecular Cloning and Nucleotide Sequence of Chicken Avidin-Related Genes 1-5", Eur. J. Biochem., vol. 220, pp. 615-621, (1994).
Van Der Hoeven et al., "Variability of Organ-Specific Gene Expression in Transgenic Tobacco Plants", Transgenic Research, vol. 3, pp. 159-165, (1994).
Morgan et al. Entomologia Experimentalis et Applicata vol. 69 No. 2 97-108 Avidin and Streptavidia as Insecticidal and Growth Inhibiting . . . , 1993.
Keinanen et al. J. Steroid Biochem. vol. 30 No. 1-6 17-21, 1988 Molecular Cloning of Three Structurally . . . .
Gordon-Kamm et al. The Plant Cell, vol. 2 603-618 Jul. 1990 Transformation of Maize Cells and Regeneration of Fertile . . . .
Cornejo et al. Plant Molecular Biology 23 567-581 1993 Activity of Maize Ubiquitin Promoter in Transgenic Rice.
Guan et al. "Expression of streptavidin gene in tobacco and its effects on bacteria", Plant Physiol. 102(1) May 1993 Abstract #XP 002017747.
Hood et al. "Commercial production of avidin from transgenic maize", In Vitro. World Congress In Vitro Biology May 21-25, 1995 Abstract #P1002.
Kulomaa et al. "Production of recombinant avidin and avidin-fusion proteins . . . ", Annual Meeting of Am. Society for Biochemistry, May 21-25 (1995), Abst. #802.
Airenne et al. "Production of recombinant avidin in Eschericia coli", Gene 144: 75-80 (1994).
During et al. Synthesis and self-assembly of a functional monoclonal antibody in transgenic Nicotiana tabacum, Plant Mol. Biol. 15: 281-293 (1990).
Goodjin et al., "Plants as Bioreactors", Trands in Biotechnology 13(9): 379-387 (1995).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Commercial production of avidin in plants does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Commercial production of avidin in plants, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Commercial production of avidin in plants will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1727678

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.