Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1992-12-15
1993-08-10
Robinson, Allen J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
560 45, 562455, 564139, 564356, 564357, 564363, 564365, C07C21300, C07C23323
Patent
active
052351033
ABSTRACT:
A process for the preparation of phenylethanolaminotetralins of formula ##STR1## wherein X is hydrogen, a halogen, a trifluoromethyl or a lower alkyl group and R.sup.o is hydrogen or a methyl group substituted by a carboxy or a lower carbalkoxy group, which comprises treating a mandelic acid with a 2-amino-7-hydroxytetralin, optionally alkylating with a lower alkyl haloacetate and reducing the amido group of the mandelamide into a methyleneamino group. The mandelamides intermediates are novel.
REFERENCES:
patent: 4707497 (1987-11-01), Cecchi et al.
Boigegrain Robert
Boveri Sergio
Cecchi Roberto
O'Sullivan P.
Robinson Allen J.
Sanofi
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