Method for the classification and monitoring of leukemias

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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436 64, 436172, 436536, G01N 33536, G01N 2164, G01N 33574

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052348164

ABSTRACT:
A method for classifying and monitoring leukemias is disclosed. The method comprises mixing cells from a patient with a plurality of fluorescently labelled monoclonal antibodies, examining the cells by means of flow cytometry, scoring the percent of positive cells in each quadrant in a two-dimensional plot of log fluorescence and comparing the scores with a standard. Monitoring of the disease also may be achieved by comparing the scores before, during and after treatment.

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