Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1997-05-20
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549268, C07D49302, A61K 31365
Patent
active
056312822
ABSTRACT:
Four triterpenes of Formula 1 (where "---" is either a single or double bond and R is H or acetate) are disclosed which are potent and selective immunosuppressive agents. These compounds have been isolated from Spachea correa root. ##STR1##
REFERENCES:
Abrue, H.D.S., Fo, R.B., Gottlieb, H.E., Shoolery, J.N. "A Nor-Triterpenoid from Lophanthera Lactescens", Phytochemistry, 29(7), 2257-2261 (1990). 1990.
Sabata, B., Connolly, J.D., Labbe, C., Rycroft, D.S. "Tetrenortriterpenoids and Related Substances. Part 19. Revised Structures of Atalantolide and Atalantin, Limonoids from the Root Bark of Atalantia monophylla Correa (Rutaceae)", J. Chem. Soc. Per 1977.
Camara Valerie J.
Daniel Mark R.
Ivy C. Warren
Merck & Co. , Inc.
Smith Lyman H.
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