Pollenosis-inducing polypeptide, process for preparing the same,

Details Pollenosis-inducing polypeptide, process for preparing the same, Pollenosis-inducing polypeptide, process for preparing the same,

1994-12-14

1997-05-20

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514 15, 514 17, 530327, 530330, 530370, 530379, 530395, 530406, 530410, 530411, 530412, 530413, 530416, 530418, 4241841, 4241851, 4242751, 4242761, 4241931, A61K 3816, A61K 3900, C07K 100

Patent

active

056312210

ABSTRACT:
A polypeptide having a molecular weight of 40,000.+-.5,000 daltons and an isoelectric point of 9.5.+-.0.5 is prepared from a cedar pollen. The polypeptide which induces pollenosis can be suitably used as desensitization agent because it induces immunoglobulin antibody which is effective for desensitization, but does not substantially induce immunoglobulin E antibody, a major factor causative of side effects including anaphylaxis shock. Therefore, the polypeptide can be advantageously used in the treatment, prevention and/or diagnosis of pollenosis.

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