Process for the preparation of tertiary carbinamines

Details Process for the preparation of tertiary carbinamines Process for the preparation of tertiary carbinamines

1992-01-10

1994-04-26

Robinson, Allen J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546213, 546194, 546329, 549 29, 549 60, 549429, 549472, 564315, 564336, 564384, 564490, 558418, 558422, 560 37, 560155, C07D40900

Patent

active

053068211

ABSTRACT:
This invention relates to a novel process for the preparation of tertiary carbinamines by double addition of organolanthanide reagents, especially organocerium reagents, to nitriles. It further relates to the preparation of such amines by the addition of organolanthanide reagents to imines.

REFERENCES:
patent: 5019650 (1991-05-01), Ciganek et al.
Imamoto et. al., J. Am. Chem. Soc., 1989, 111, 4392-4398.
Gauthier et. al, J. of organometallic Chem., 140, 1977, 245-255.
Krimen and Cota, Org. React., 1969, 17:213.
Gautier et al., Bull. Soc. Chim. France., 1968, 2916.
Layer, Chem. Rev., 1963, 63:489.
Alvernhe and Laurent, Tetrahedron Lett., 1973, 1057.
Henze et al., J. Am. Chem. Soc., 1943, 65:87.
Henze et al., J. Am. Chem. Soc., 1943, 65:1422.
Henze et al., J. Am. Chem. Soc., 1951, 73:4915.
Allen and Henze, J. Am. Chem. Soc., 1939, 61:1790.
Henze and Swett, 1951, 73:4918.
Chastrette et al., Tetrahedron Lett., 1977, 1:23.
Chastrette and Axiotis, Synthesis, 1980, 889.
Amouroux and Axiotis, Synthesis, 1981, 270.
Neuvonen and Pihlaja, J. Chem. Soc. Perkin Trnsl. II., 1988, 461.
Woodburn and Lathroum, J. Org. Chem., 1954, 19:285.
Pornet and Miginiac, Bull. Soc. Chim. France, 1975, 841.
Davis and Mancinelli, J. Org. Chem., 1977, 42(2):398.
Lipshutz et al., Tetrahedron Lett., 1986, 27(36):4241.
Gauthier et al., J. Organomet. Chem., 1977, 140:245.
Rehberg and Henze, J. Am. Chem. Soc., 1941, 63:2785.
Imamoto et al., J. Org. Chem., 1984, 49:3904.
Imamoto et al., J. Am. chem. Soc., 1989, 111:4392.
Roetz et al., Agnew. Chem. Int. Ed. Engl. 1991, 30:103.
Denmark et al., J. Am. Chem. Soc., 1987, 109:2224.
Weber et al., Synlett, 1989, p. 20.
Fujioka et al., Chem. Pharm. Bull., 1989, 37:602.
Ukaji et al., Chemistry Lett., 1991, p. 173.
Patai, ed., Chemistry of the Carbon-Nitrogen Double Bond, 1970, ch. 6-8.

Affiliated with

Also associated with

Rating

Process for the preparation of tertiary carbinamines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of tertiary carbinamines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of tertiary carbinamines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1712661