Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1977-08-26
1979-06-05
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
424180, 536 18, 536 53, C07H 1900, A61K 3170
Patent
active
041574397
ABSTRACT:
Novel nitrosourea derivatives are provided which possess a high inhibitory activity against the leukemia and tumors with a low toxicity and a good stability against humidity and which are useful for pharmaceutical purposes. The compounds have the structure: ##STR1## wherein R.sup.1 represents hydroxyl or alkanoyloxy containing 2-4 carbon atoms; R.sup.2 represents hydrogen or alkanoyl containing 2-4 carbon atoms; R.sup.3 represents alkanoyl containing 2-4 carbon atoms; and R.sup.4 represents alkyl or halo-substituted alkyl containing 1-4 carbon atoms.
REFERENCES:
patent: 3577406 (1971-05-01), Hessler
patent: 4022963 (1977-05-01), Deutsh
Brown Johnnie R.
Hazel Blondel
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