Leukotriene antagonists useful for treating dermatoses

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514 13, 514 14, 514 15, 514 16, 514 17, 514 18, 514 19, 514252, 514318, 514332, 514340, 514343, 514346, 514347, 514351, 514521, 514520, 514570, 5142395, 5142392, 5142388, 5142378, 5142335, 5142328, A61K 3119, C07D25704

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059143401

ABSTRACT:
This invention provides methods for the treatment or inhibiting of dermatitis which comprises administering to a mammal in need thereof an effective amount of a compound having activity as a leukotriene B.sub.4 antagonist.

REFERENCES:
patent: 4885309 (1989-12-01), Welton
patent: 5001136 (1991-03-01), Walker
patent: 5462954 (1995-10-01), Baker et al.
Fogh, et al., J. Allergy Clin. Immunol., 83: 450-455 (1989).
Barr, et al., British Journal of Dermatology, III: 23-28 (1984).
Czaretzki, Clin. Exp. Immunol., 54: 486-492 (1983).
Rosenbach, et al., British Journal of Dermatology, 113: Supplement 28: 157-167 (1985).
Sawyer, J. Scott, Exp. Opin. Invest. Drugs 5(1) :73-77 (1996).
Sawyer, J. Scott, Drugs of the Future, 21 (6):610-614 (1996).

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