Mammallian sex comb on midleg (mammalian SCM) acts as a tumor su

Chemistry: molecular biology and microbiology – Vector – per se

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536 231, C12N 1500, C07H 2102

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059142669

ABSTRACT:
Mammalian Scm gene and amino acid sequences encoded by the mammalian Scm gene, are described. The mammalian Scm gene and gene products are useful for diagnostic and therapeutic applications in proliferative and developmental disorders. Modulators of mammalian Scm can be identified using the dislcosed genes. The modulators can be used in the context of cancer therapy or a treatment of a developmental disorder. Scm is also useful for inducing differentiation in a population of progenitor cells.

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