Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-12-05
1999-06-22
Huff, Sheela
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 435 723, 536 231, C12P 2106, C12N 1500, G01N 33574, C07H 2102
Patent
active
059142499
ABSTRACT:
The invention provides two human cell-cycle phosphoproteins, referred to collectively as "CECYP" and individually as "CECYP-1" and "CECYP-2" , and polynucleotides which identify and encode CECYP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of CECYP.
REFERENCES:
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Zimmer, M., et al., "Cloning of the VASP (Vasodilater-Stimulated Phosphoprotein) Genes in Human and Mouse: Structure, Sequence, and Chromosomal Localization," Genomics, 36(0457):227-233 (1996) (GI 1617319 & GI 1621246) (1997).
Wilson, R., et al., (GI 790404), GenBank Sequence Database (Accession Z49130), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894 (1997).
Wilson, R., et al., (GI 790397), GenBank Sequence Database (Accession Z49130), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894 (1997).
Zimmer, M., et al., (GI 1617319), GenBank Sequence Database (Accession X98533), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894 (1996).
Zimmer, M., et al., (GI 1621246), GenBank Sequence Database (Accession X98534), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894 (1996).
Stukenberg, P.T., et al., (GI 2072296), GenBank Sequence Database (Accession U95098), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894 (1994).
Stukenberg, P.T., et al., (GI 2072295), GenBank Sequence Database (Accession U95098), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894 (1997).
Girault, J., et al., "Differential Expression of ARPP-16 and ARPP-19, Two Highly Related cAMP-Regulated Phosphoproteins, One of Which is Specifically Associated with Dopamine-Innervated Brain Regions," The Journal of Neuroscience, 10(4):1124-1133 (1990).
Corley Neil C.
Lal Preeti
Shah Purvi
Eyler Yvonne
Huff Sheela
Incyte Pharmaceuticals Inc.
Mohan-Peterson Sheela
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