Prevention and treatment of periodontal disease with alendronate

Details Prevention and treatment of periodontal disease with alendronate Prevention and treatment of periodontal disease with alendronate

1991-12-17

1993-12-14

Rose, Shep

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

424 49, 424 54, 514900, 514902, A61K 722, A61K 3342, A61K 3166

Patent

active

052703657

ABSTRACT:
This invention claims a method for treating periodontal disease in mammals, including humans, by administering an effective amount of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or a pharmaceutically acceptable salt including the monosodium salt tridydrate (alendronate) of the formula: ##STR1## The compounds are useful in the treatment of alveolar bone loss associated with peridontitis and periodontal disease.

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