Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides

Details Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides

1993-01-26

1993-12-14

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548468, 548406, 514212, 5142275, 5142352, 514323, 514339, 540602, 544 62, 544144, 546201, 546273, A61K 3140, C07D40306

Patent

active

052703312

ABSTRACT:
Antiinflammatory and analgesic oxindole prodrugs of the formula ##STR1## wherein R.sup.10, R.sup.11, R.sup.12 and R.sup.13 are hydrogen, alkyl or halogen and R is methyleneoxyalkanoyl, methyleneoxyalkenoyl or alkenoyl.

REFERENCES:
patent: 4556672 (1985-12-01), Kadin
patent: 5118703 (1992-06-01), Reiter et al.

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