Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-06-21
1995-05-09
Morris, Patricia L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548252, 548253, 548254, A61K 31415, C07D40310
Patent
active
054140080
ABSTRACT:
Imidazolyl-substituted phenylpropionic and cinnamic acid derivatives are prepared by reacting appropriate benzyl compounds with imidazoles and optionally varying the substituents. The imidazolyl-substituted phenylpropionic and cinnamic acid derivatives can be used as active compounds in medicaments, in particular in the treatment of arterial hypertension and atherosclerosis.
REFERENCES:
patent: 4355040 (1982-10-01), Furukawa et al.
patent: 4946841 (1990-08-01), Baader et al.
patent: 5168956 (1992-12-01), Namioka
patent: 5183810 (1993-02-01), Greenlee et al.
Journal of the American Chemical Society/99.9/Apr. 27, 1977, "Inductive Enhancement of Aryl Participation", Joseph Lambert, et al. pp. 3059-3067.
The Journal of Cell Biology, vol. 50, 1971, pp. 172-186, "The Smooth Muscle Cell", Russell Ross.
Russian Chemical Reviews, Usepekhi Khimii, Jan. 1963, pp. 1-20, "Mechanisms of the Hydrolysis of Aromatic Sulphonyl Chlorides . . . ".
J. March, Advanced Organic Chemistry, Second Edition, pp. 836-841. (1977).
N. Leo Benoiton, et al. Int. J. Peptide Protein Res. 17, 1981, pp. 197-204.
Journal of Biological Chemistry, Frerman et al., J. Biol. Chem. 258, pp. 7087-7093. (1983).
Sheehan, Ledis/Total Synthesis of Etamycin, 1973, pp. 875-879.
Beuck Martin
Dressel Jurgen
Fey Peter
Hanko Rudolf H.
Hubsch Walter
Bayer Aktiengesellschaft
Morris Patricia L.
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