Pyridinylmethyl-substituted pyridines and pyridones

Details Pyridinylmethyl-substituted pyridines and pyridones Pyridinylmethyl-substituted pyridines and pyridones

1994-04-29

1995-05-09

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514332, 514335, 546255, 546256, 546261, 546262, 546264, 546266, C07D40114, A61K 3144, A61K 3150, A61K 3153

Patent

active

054140030

ABSTRACT:
Pyridinylmethyl-substituted pyridines and pyridones are prepared by reacting pyridine- or pyridone-substituted halogenopyridines with tetrazolylphenylboronic acids. The substances according to the invention can be used as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.

REFERENCES:
patent: 5128327 (1992-07-01), Chakravarty et al.
patent: 5149699 (1992-09-01), Ellingboe et al.
patent: 5155117 (1992-10-01), Reitz
patent: 5196537 (1993-03-01), Reitz
E. L. Eliel, Stereochemistry of Carbon Compounds, McGraw Hill, 1962, 6 pgs.
The Journal of Cell Biology, vol. 5, 1971, pp. 172-186; "The Smooth Muscle Cell . . . ", R. Ross.

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