Chemistry of inorganic compounds – Phosphorus or compound thereof – Oxygen containing
Patent
1988-05-02
1989-07-18
Doll, John
Chemistry of inorganic compounds
Phosphorus or compound thereof
Oxygen containing
423309, 423311, C01B 2532
Patent
active
048491934
ABSTRACT:
This invention relates to the manufacture of hydroxylapatite in a through-solution process wherein monobasic calcium phosphate is reacted with a calcium hydroxide solution. In a preferred embodiment, an acidic premix is formed by reacting phosphoric acid and calcium hydroxide with high shear agitation in a first stage, and thereafter reacting the acidic premix with a saturated solution of calcium hydroxide also under high shear agitation in a second stage. The second stage reaction is carried out in an alkaline solution by carefully metering the acid premix into the calcium hydroxide solution whereby the pH of the solution is maintained above 11 until the reaction is near completion. It is particularly preferred to use a stoichiometric portion of calcium hydroxide in carrying out the reactions. After the hydroxylapatite precipitate is recovered, it may be sintered at a temperature between about 700.degree. C. and 1100.degree. C. for about 5 to 30 minutes to form a crystalline hydroxylapatite.
REFERENCES:
patent: 3787900 (1974-01-01), McGee
patent: 4097935 (1978-07-01), Jarcho
patent: 4324772 (1982-04-01), Conn et al.
patent: 4481175 (1984-11-01), Iino et al.
patent: 4497075 (1985-02-01), Niwa et al.
patent: 4516276 (1985-05-01), Mittelmeier et al.
patent: 4518430 (1985-05-01), Brown et al.
patent: 4548959 (1985-10-01), Nagai et al.
patent: 4612053 (1986-09-01), Brown et al.
patent: 4629464 (1986-12-01), Takata et al.
patent: 4673355 (1987-06-01), Farris et al.
patent: 4721615 (1988-01-01), Griffith et al.
patent: 4781904 (1988-11-01), Tagaya et al.
patent: 4794171 (1988-12-01), Tagaya et al.
Palmer Jay W.
Rosenstiel Terry L.
Didrick Robert M.
Doll John
Langel Wayne A.
Lorenzen John M.
Robinson Robert H.
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