Peptide library and screening method

Details Peptide library and screening method Peptide library and screening method

1991-10-16

1993-12-14

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

43525233, 4353201, 935 11, C12Q 168, C12Q, C12N 121, C12N 1572

Patent

active

052701700

ABSTRACT:
A random peptide library constructed by transforming host cells with a collection of recombinant vectors that encode a fusion protein comprised of a DNA binding protein and a random peptide and also encode a binding site for the DNA binding protein can be used to screen for novel ligands. The screening method results in the formation of a complex comprising the fusion protein bound to a receptor through the random peptide ligand and to the recombinant DNA vector through the DNA binding protein.

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