Chemistry: molecular biology and microbiology – Maintaining blood or sperm in a physiologically active state... – Using bacteria or actinomycetales
Patent
1992-03-02
1994-02-22
Wityshyn, Michael G.
Chemistry: molecular biology and microbiology
Maintaining blood or sperm in a physiologically active state...
Using bacteria or actinomycetales
424 90, 424530, 604 4, 604 20, A01N 102, A61K 4100, A61M 3700, A61N 130
Patent
active
052886050
ABSTRACT:
Methods and compositions are described for treating contaminants in material intended for in vivo use, and in particular blood and blood products for human use. Contaminants in blood cell preparations are inactivated using 8-methoxypsoralen prior to long term storage and transfusion.
REFERENCES:
patent: 4124598 (1978-11-01), Hearst et al.
patent: 4169204 (1979-09-01), Hearst et al.
patent: 4196281 (1980-04-01), Hearst et al.
patent: 4321919 (1982-03-01), Edelson
patent: 4727027 (1988-02-01), Wiesehahn et al.
patent: 4748120 (1988-05-01), Wiesehahn
patent: 4878891 (1989-11-01), Judy
patent: 4944920 (1990-07-01), Rubinstein
patent: 4960408 (1990-10-01), Klainer
patent: 4997577 (1991-03-01), Stewart
patent: 5011695 (1991-04-01), Dichtelmuller et al.
Lin Lily, use of 8 Mop & Long Wavelength UV Radiation . . . Blood vol. 74 #1 Jul. 1989 pp,. 517-525.
Murphy and Gardner, New Eng. J. Med. 280:1094 (1969).
B. J. Grossman et al., Transfusion 31:500 (1991).
B. A. Myhre, JAMA 244:1333 (1980).
J. M. Heal et al., Transfusion 27:2 (1987).
D. H. Buchholz, et al., Transfusion 13:268 (1973).
D. H. Buchholz, et al., New Eng. J. Med. 285:429 (1971).
J. F. Morrow et al., JAMA 266:555 (1991).
G. D. Cimino et al., Ann. Rev. Biochem. 54:1151 (1985).
Hearst et al., Quart. Rev. Biophys. 17:1 (1984).
S. T. Isaacs et al., Biochemistry 16:1058 (1977).
S. T. Isaacs et al., Trends in Photobiology (Plenum) pp. 279 94 (1982).
J. Tessman et al., Biochem. 24:1669 (1985).
H. J. Alter et al., The Lancet (ii:1446) (1988).
L. Lin et al., Blood 74:517 (1989).
Hyde and Hearst, Biochemistry 17:1251 (1978).
Thompson et al., J. Mol. Biol. 147:417 (1981).
Thompson et al., Biochemistry 21:1363 (1982).
R. Y. Dodd, In: Transfusion Medicine in the 1990's (American Assoc. Blood Banks 1990) (S. J. Nance, ed.).
M. Artuc et al., Brit. J. Derm. 101:669 (1979).
M. J. Metzelaar, Studies on the Expression of Activation-Markers on Human Platelets (Thesis 1991).
Goddard, D., Jacobs, S. I., Manohitharajah S. M., "The Bacteriological Screening of Platelet Concentrates Stored at 22 C," Transfusion 13:103 (1973).
Meek, E. et al., "Bacterial Proliferation in Human Platelet Concentrates Stored in Plasma or Artificial Medium," P.F.1.90 (ISBT) (1988).
Cordle, D., Koepke, J. A., and Koontz, F. P., "The Sterility of Platelet and Granulocyte Concentrates Collected by Discontinuous Flow Centrifugation," Transfusion 30:105 (1980).
Dodd, R. Y. et al., "Inactivation of Viruses in Platelet Suspensions that Retain Their in Vitro Characteristics: Comparison of Psoralen-ultraviolet A and Merocyanine 540 Visible Light Methods," Transfusion 31:483 (1991).
Kasha, M., "Transmission Filters for the Ultraviolet," Jour. Optical Soc. Amer. 38:929 (1948).
Ben-Hur, E., et al., "Measurement of DNA Crosslinks by S1 Nuclease: Induction and Repair in Psoralen-Plus-360 nm Light Treated Escherichia coli," Photochemistry and Photobiology 29: 921 (1979).
Bordin, F. et al., "DNA Repair and Recovery in Escherichia coli after Psoralen and Angelicin Photosensitization," Biochimica et Biophysica Acta 447:249 (1976).
Bridges, B. A., "8-Methoxypsoralen and Radiation Damage in Bacteria," Int. Jour. Radiation Bio. 20:185 (date not available).
Fujita, H. and Kakishima, H., "Photobiological Activities of 5-alkoxypsoralens with Respect to the Action on Escherichia coli," Photochemistry and Photobiology 43:221 (1986).
Hass, B. S. and Webb, R. B., "8-Methoxypsoralen Effects on Survival and Repair of Escherichia Coli after Ultraviolet Irradiation: Action Spectra," Radiation Research 80:170 (1979).
Belogurov, A. A. and Zavil'gel'skii, G. B. "Mechanism of the Inactivation Action of the Photosensitizer 8-Methoxypsoralen on Bacteria and Bacteriophages," Sovgenet 14:219 (1978).
Margolis-Nunno H., et al,, "Virus sterilization in Platelet Concentrates with Psoralen and Ultraviolet A Light in the Presence of Quenchers," Transfusion 32:541 (1992).
Mohr, H. et al., Infusionstherapie 19:79 (1992).
Cimino George D.
Corash Lawrence
Hanson Carl V.
Isaacs Stephen T.
Lin Lily
Carroll Peter G.
Gitomer Ralph
Steritech, Inc.
Wilke Kathryn P.
Wityshyn Michael G.
LandOfFree
Methods for inactivating bacteria in blood preparations with 8-m does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for inactivating bacteria in blood preparations with 8-m, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for inactivating bacteria in blood preparations with 8-m will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-170203