Rh blood group antigen compositions and methods of use

Chemistry: analytical and immunological testing – Including chromatography

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436518, 436523, 436824, 435 4, 435 71, 435332, 4353441, 435337, 435343, G01N 3090

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active

058405852

ABSTRACT:
Disclosed are novel protein and peptide compositions comprising soluble and bound forms of immunologically-active blood group antigens including mammalian Rh antigens. In preferred embodiments methods for the isolation and purification of serologically-active human Rh antigens such as D, c, C, E, and e are disclosed. Also disclosed are methods for the adsorption of immunologically-active Rh antigens to solid supports. Diagnostic kits, methods, and devices for the detection of Rh antibodies in clinical and non-clinical samples are also disclosed. Devices, compositions and methods for the isolation, purification and quantitation of anti-Rh antibodies from solution are also provided.

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