Stabilized antimicrobial compositions

Details Stabilized antimicrobial compositions Stabilized antimicrobial compositions

1989-05-03

1991-12-03

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514772, 514788, 514970, A01N 3718

Patent

active

050701053

ABSTRACT:
Stabilized antimicrobial compositions containing an antimicrobial amount of 2,2-dibromo-3-nitrilopropionamide in water miscible organic solvents. The stabilizer used is selected from chain-breaking antioxidants of the phenolic or amine type in an amount in the range of 0.001% to 0.5% by weight of the composition. Typical examples of stabilizers are: 2,6-di-tert-butyl-p-cresol; 4,4'-bis-(2,6-di-tert-butylphenol); 2,6-di-tert-butyl-.alpha.-methoxy-p-cresol and N-phenyl-.beta.-naphthylamine. The antimicrobial compositions also contain one or more water miscible organic solvents selected from those known in the art, in which the 2,2-dibromo-3-nitrilopropionamide is at least partially soluble. The compositions according to the present invention are characterized by their outstanding stability, compared with formulations which do not contain these stabilizers.

REFERENCES:
patent: 4163795 (1979-08-01), Burk
patent: 4163796 (1979-08-01), Burk
patent: 4163797 (1979-08-01), Burk et al.
patent: 4163798 (1979-08-01), Burk et al.
patent: 4190668 (1980-02-01), Burk et al.
Chem. Abstracts 66:76585c (1967).
Chem. Abstracts 76:15560a (1972).
Chem. Abstracts 77:1832z (1972).
Chem. Abstracts 78:86930y (1973).
Chem. Abstracts 78:112063g (1973).

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