Des-(ser.sup.13)-srif and intermediates

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424177, C07C10352, A61K 3700

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active

039337847

ABSTRACT:
The tridecapeptide H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Cys-OH, its oxidized form and intermediates obtained in such synthesis are described. This tridecapeptide inhibits the secretion of the hormone somatotropin (growth hormone).

REFERENCES:
patent: 3842066 (1974-10-01), McKinley et al.
patent: 3842067 (1974-10-01), Sarantakis
patent: 3882098 (1975-05-01), Sarantakis

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