Substituted dihydroxy-bis-[5-hydroxy-2(5H)-furanone-4-yl]-alkane

Details Substituted dihydroxy-bis-[5-hydroxy-2(5H)-furanone-4-yl]-alkane Substituted dihydroxy-bis-[5-hydroxy-2(5H)-furanone-4-yl]-alkane

1991-04-30

1993-07-06

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549313, C07F 906, C07F 928, C07D30760

Patent

active

052255719

ABSTRACT:
Compounds of the formula ##STR1## in which R.sub.1 is H or alkyl of 1 to 20 carbons, CO--R.sub.2, CO--O--R.sub.2, CO--NH--R.sub.2, or PO(OR.sub.2).sub.2 or PO(OR.sub.2)R.sub.2, where R.sub.2 independently is H, alkyl of 1 to 20 carbons, phenyl, or lower alkyl substituted phenyl or halogen substituted phenyl; n is an integer between 8 to 14; Y is H, alkyl having 1-20 carbon atoms, aryl[lower alkyl], aryl, lower alkyl[aryl], alkenyl containing one or more olephinic bonds and 1-20 carbon atoms, CO--R.sub.3, CO--OR.sub.3, CONHR.sub.3, SO.sub.2 R.sub.3, SO.sub.2 NHR.sub.3 where R.sub.3 is aryl[lower alkyl], aryl, lower alkyl[aryl], alkenyl containing one or more olephinic bonds and 1-20 carbon atoms, further Y is PO(OH).sub.2, PO(OH)OR.sub.4, PO(OH)R.sub.4 PO(OR.sub.4).sub.2, where R.sub.4 is independently alkyl of 1-20 carbons or phenyl, have anti-inflammatory activity.

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