Thiazolidine-2,4-dione compound and method of treatment of diabe

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548183, A61K 31425

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active

052254267

ABSTRACT:
A novel compound is proposed which is effective in curing various complications as with catarat, retinopathy, neurotic disorder, and renal disorder. The thiazolidine-2,4-dione compound represented by the following general formula I combines an action to inhibit aldose reductase and an action to depress blood sugar and manifests an efficacy in the cure of various complications as with catarat, retinopathy, neurotic disorder, and renal disorder. ##STR1## wherein R.sup.1 is a hydrogen atom or a methyl group.

REFERENCES:
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patent: 4725610 (1988-02-01), Meguro et al.
patent: 4948900 (1990-08-01), Iijima et al.
patent: 5061717 (1991-10-01), Clark et al.
Chemical Abstract vol. III, No. 23, Abstract No. 214230 to Chin et al.

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