Technetium-99m labeled somatostatin-derived peptides for imaging

Details Technetium-99m labeled somatostatin-derived peptides for imaging Technetium-99m labeled somatostatin-derived peptides for imaging

1991-09-10

1993-07-06

Stoll, Robert L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

5303913, 530402, 530311, 530350, A61K 4902, A61K 3702

Patent

active

052251802

ABSTRACT:
The invention relates to radiolabeled imaging of a mammalian body. The invention in particular provides for reagents labeled with technetium-99m for such imaging. The invention specifically provides somatostatin, somatostatin derivatives, somatostatin analogues or peptides that bind to the somatostatin receptor and contain at least 2 cysteine residues that form a disulfide or wherein the disulfide is reduced to the sulfhydryl form that are directly labeled with technetium-99m and that can be targeted to specific sites within a mammalian body for imaging.

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