Polymerization and copolymerization of proteins

Details Polymerization and copolymerization of proteins Polymerization and copolymerization of proteins

1989-02-06

1992-07-28

Nucker, Christine

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Stablizing an enzyme by forming a mixture, an adduct or a...

435189, 435190, 435192, 435194, 435207, 435964, 530345, 530362, 530363, 530367, 5303919, 530404, 530405, 530408, 530409, 530807, 530812, C12N 996, C07K 1702

Patent

active

051340712

ABSTRACT:
A method for producing a polyprotein having at least 10 units, and often as many as 50 to 100 and more units held together by sulfur to sulfur or sulfur to carbon bonds is disclosed. Each unit comprises a protein and one or more heterobifunctional reagents. One functional group of the reagent is capable of forming a covalent bond with an amino group, permitting the reagent to bind to a protein. The other functional group of the reagent is capable of forming a covalent bond with a thiol group so as to form the covalent sulfur-carbon or sulfur-sulfur bond with another heterobifunctional reagent bonded to another protein.

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