Treating mammalian subject sensitive to indomethacin ulcerogenis

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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424274, A61K 3162, A61K 31405

Patent

active

042006317

ABSTRACT:
Ulcer production in animals is prevented during prolonged antiphlogistic treatment with ulcerogenic quantities of indomethacin by using it in a composition of 1 part of indomethacin to 7.5 to 25 parts, preferably 10 parts by weight of a salicylate. Indomethacin is the most potent ulcerating compound among approved non-steroid antiinflammatory agents.

REFERENCES:
Hultmark et al.-Chem. Abst. vol. 83 (1975), p. 141,706k.
Gietka et al.-Chem. Abst. vol. 82 (1975), p. 291p.

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