MTBX protein and nucleic acid molecules and uses therefor

Details MTBX protein and nucleic acid molecules and uses therefor MTBX protein and nucleic acid molecules and uses therefor

1998-11-09

2000-03-14

Cochrane Carlson, Karen

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 435325, 4352523, 536 231, C12P 2106, C12N 1500, C07H 1700

Patent

active

06037148&

ABSTRACT:
Novel MTbx polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length MTbx proteins, the invention further provides isolated MTbx fusion proteins, antigenic peptides and anti-MTbx antibodies. The invention also provides MTbx nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a MTbx gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

REFERENCES:
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Blast.TM. Search Using T-Box Gene.
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GenBank Accession No. AA083564 for Stratagene hNT neuron (#937233) Homo sapiens cDNA clone Image:546980 5'.
GenBank Accession No. AA083565 for Stratagene hNT neuron (#937233) Homo sapiens cDNA clone Image:546980 3'.
GenBank Accession No. AA104395 for life Tech mouse embryo 15 5dpc 10667012 Mus musculus cDNA clone Image:556226 5'.
GenBank Accession No. AA323074 for Cerebellum II Homo sapiens cDNA 5' end.
GenBank Accession No. AA325492 for Cerebellum II Homo sapiens cDNA 5' end similar to Brachyury protein (T protein).
GenBank Accession No. AA331172 for Embryo, 8 week I Homo sapiens cDNA 3'.
GenBank Accession No. AA331173 for Embryo, 8 week I Homo sapiens cDNA 5'.
GenBank Accession No. for AA331789 for Embryo, 8 week I Homo sapiens cDNA 5' end similar to Brachyury protein (T protein).
GenBank Accession No. AA332234 for Embryo, 8 week I Homo sapiens cDNA 5' end similar to lethal(1) optomotor-blind gene product.
GenBank Accession No. AA333545 for Embryo, 8 week I Homo sapiens cDNA 5' end similar to Brachyury protein (T protein).
GenBank Accession No. AA606650 for Knowles Solter mouse blastocyst B1 Mus musculus cDNA clone Image:1005768 5'.
GenBank Accession No. AA606660 for Knowles Solter mouse blastocyst B1 Mus musculus cDNA clone Image:1005792 5'.
GenBank Accession No. AA961425 for NCI.sub.-- CGAP.sub.-- GC3 Homo sapiens cDNA clone Image:1599514 3'.
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