Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector
Patent
1996-11-14
1999-06-08
Saunders, David
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
424449, 424450, 4242041, 4242341, 4242651, 4242691, 4242741, 4242771, 4242791, 4242821, 4242831, 424810, 424812, A61K 3900, A61K 39002, A61K 3902, A61K 3912
Patent
active
059103060
ABSTRACT:
A transdermal liposome system delivers antigen to immune cells without perforation of the skin, and induces an immune response in an animal or human. The system uses liposomes to deliver a variety of antigens which can elicit an antigen-specific immune response (e.g., humoral and/or cellular effectors) after topical application of a formulation containing liposomes and antigen to intact skin of the animal or human.
REFERENCES:
patent: 4196191 (1980-04-01), Almeida
patent: 4455142 (1984-06-01), Martins
patent: 4484923 (1984-11-01), Amkraut
patent: 4876278 (1989-10-01), Taylor
patent: 4877612 (1989-10-01), Berger
patent: 4921757 (1990-05-01), Wheatley
patent: 4929442 (1990-05-01), Powell
patent: 5008050 (1991-04-01), Cullis
patent: 5059421 (1991-10-01), Loughrey
patent: 5169637 (1992-12-01), Lenk
patent: 5200393 (1993-04-01), Weiner
patent: 5256422 (1993-10-01), Albert
patent: 5260066 (1993-11-01), Wood
patent: 5326790 (1994-07-01), Thornfeldt
patent: 5332576 (1994-07-01), Mantelle
patent: 5340588 (1994-08-01), Domb
patent: 5352449 (1994-10-01), Beltz
patent: 5464386 (1995-11-01), Hofmann
patent: 5601827 (1997-02-01), Collier
patent: 5607691 (1997-03-01), Hale
patent: 5733572 (1998-03-01), Unger
Hsiung, GD and Fong, CKY, Diagnostic Virology, 3rd ed., Yale Univ. Press, New Haven, CT, pp. 29-34, 1982.
Lane, HC, Whalen G, and Fauci AS, In vitro evaluation of human lymphocyte function, In: Cellular Immunology, DM Weir, ed., Blackwell Scientific Pub. Boston, MA, pp. 66.5-66.7, 1986.
Becker, Experimental Dermatology, 2:63-69, 1993.
Blauvelt, Journal of Investigative Dermatology, 104:293-296, 1995.
Bowen, Immunology, 81:338-342, 1994.
Chin, Veterinary Microbiology, 43:21-32, 1995.
Chin, Journal of Biotechnology, 44:13-19, 1996.
Condon, Nature Medicine, 2:1122-1128, 1996.
Enk, Journal of Immunology, 151:2390-2398, 1993.
Goodnow, Immunological Reviews, 156:5-10, 1997.
Knop, International Archives of Allergy and Immunology, 107:231-232, 1995.
Mahmoud, Science, 246:1015-1022, 1989.
Peters, Immunology Today, 17:273-278, 1996.
Schwarzenberger, Journal of Investigative Dermatology, 106:553-558, 1996.
Stacey, Journal of Immunology, 157:2116-2122, 1996.
Steinman, Immunological Review, 156:25-37, 1997.
Stingl, Immunological Series, 46:3-72, 1989.
Udey, Clinical and Experimental Immunology, 107(suppl. 1):6-8, 1997.
Alving, Vaccine 4:166-172, 1986.
Alving, Journal of Immunological Methods, 140:1-13, 1991.
Alving, Immunobiol., 187:430-446, 1993.
Alving, NY Acad. Sci., 690:265-275, 1993.
Alving, AIDS Research and Human Retroviruses, 10:S91-S94, 1994.
Alving, Immunological Reviews, No. 145, 5-31, 1995.
Egbaria, Advanced Drug Delivery Reviews, 5:287-300, 1990.
Fleisher, Life Sciences, 57:1293-1297, 1995.
Glenn, Immunology Letters, 47:73-78, 1995.
Gupta, Vaccine, 13:1263-1276, 1995.
de Haan, Vaccine, 13:1320-1324, 1995.
Korting, Journal of the American Academy of Dermatology, 25:1068-1071, 1991.
Korting, British Journal of Dermatology, 132:571-579, 1995.
Mengiardi, Vaccine, 13:1306-1315, 1995.
Mezei, Life Sciences, 26:1473-1477, 1980.
Moghimi, J. Microencapsulation, 10:155-162, 1993.
Norimatsu, Vaccine, 13:1325-1329, 1995.
Paul, Vaccine Research, 4:145-164, 1995.
Paul, Eur. J. Immunol., 25:3521-3524, 1995.
Powers, Vaccine, 13:1330-1335, 1995.
Ranade, J. Clin. Pharmacol., 31:401-418, 1991.
Rao, Infection and Immunity, 63:2396-2402, 1995.
Sauzet, Vaccine, 13:1339-1345, 1995.
Schafer-Korting, Journal of the American Academy of Dermatology, 21:1271-1275, 1989.
Verma, Biochimica et Biophysica Acta, 1066:229-238, 1991.
Verma, Infection and Immunity, 60:2438-2444, 1992.
Vutla, Journal of Pharmaceutical Sciences, 85:5-8, 1996.
Wang, The Journal of Immunology, 156:4079-4082, 1996.
Wang, The Journal of Immunology, 154:2784-2793, 1995.
Wassef, Immunomethods, 4:217-222, 1994.
Weiner, Antimicrobial Agents and Chemotherapy, 33:1217-1221, 1989.
White, Vaccine, 11:1341-1346, 1993.
White, Vaccine, 13:1111-1122, 1995.
Yasutomi, Journal of Virology, 69:2279-2284, 1995.
Zellmer, Biochimica et Biophysica Acta, 1237:176-182, 1995.
Alving, In: Liposome Technology, 2nd Ed. (Gregoriadis, ed.), CRC Press, pp. 317-343, 1993.
Small, In: Handbook of Lipid Research, Plenum, 4:43-87.
Small, In: Handbook of Lipid Research, Plenum, 4:89-96.
Alving Carl R.
Glenn Gregory M.
Saunders David
The United States of America as represented by the Secretary of
Tung Mary Beth
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