Methods for using proanthocyanidin polymers having antiviral act

Details Methods for using proanthocyanidin polymers having antiviral act Methods for using proanthocyanidin polymers having antiviral act

1994-02-09

1996-02-27

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Monomer contains oxygen

4241951, A01N 6500, A61K 31765

Patent

active

054946611

ABSTRACT:
The present invention provides for proanthocyanidin polymers with significant antiviral activity. The proanthocyanidin polymers can be chemically synthesized or can be isolated from a Croton or a Calophyllum plant species. The present invention encompasses methods of using proanthocyanidin polymers in treating warm-blooded animals, including humans, infected with a respiratory virus.

REFERENCES:
patent: 4698360 (1987-10-01), Masquelier
patent: 4806659 (1989-02-01), Itsuo et al.
patent: 4863956 (1989-09-01), Gabetta et al.
patent: 4925871 (1990-05-01), Gabetta et al.
Rao--Indian J. of Plant Physiology vol. XXIX, No. 3, 1986 pp. 278-280.
Foo et al Phytochem. of . . . Polymers 1980 vol. 19 pp. 1747-1754.
Newman et al Mag. Resonance in Chemistry, vol. 25, 118-124 (1987).
Vaisberg et al. Planta Medica 55 1989 pp. 141-143.
Beladi et al Ann. N.Y. Acad. Sic. 1977 (284) pp. 358-364.
Delcour et al., 1983, Chem. Soc. Perkin Trans. 1:1711-17.
Czochanska, et al. 1979, J.C.S. Chem. Comm. 375-77.
Jones et al., 1978, Physiochemistry 15:1407-09.
Mattice and Porter, 1984, Phytochemistry 23:1309-11.
Porter et al., 1982, J.C.S. Perkin 1:1217-21.
Thompson et al., 1972, J.C.S. Perkin 1:1387-99.
Hemingway et al., 1982, J.C.S. Perkin 1:1209-16.
Fletcher et al., J.C.S. Perkin 1:1628-37.
Morimoto et al., 1986, Chem. Pharm. Bull. 34:633-42.
Gujer et al., 1986, Physiochemistry 25: 1431-36.
Bettolo and Scarpati, 1979, Phytochemistry, 18:520.
Pieters et al., 1990, Phytochemistry, 29(1):348-349.
Perdue et al., 1979, J. Pharm. Sci., 68:124-25.
McManus et al., 1981, J.C.S. Chem. Comm., 309-11.
Englund et al., 1988, Ann. Int. Med., 1:203-08.
Edwin Haslam, in Plant Polyphenols--Vegetable Tannins Revisited, Cambridge University Press, New York, ch. 2 pp. 14-89, Pranthocyanidins.
Misra and Dixit, 1983, Ind. J. Pharm. Sci., 216-19.
Cai et al., 1991, Phytochemistry, 30:2033-40.
G. Wayne McGraw, "Reactions at the A-Ring of Proanthocyanidins" in Chemistry and Significance of Condensed Tannins, Hemingway and Karchesy eds., Plenum Press, New York, pp. 227-283.
Richard W. Hemingway, "Structural Variations in Proanthocyanidins and Their Derivatives" in Chemistry and Significance of Condensed Tannins, Hemingway and Karchesy eds., Plenum Press, New York, pp. 83-107.
Peter E. Laks, "Condensed Tannins as a Source of Novel Biocides" in Chemistry and Significance of Condensed Tannins, Hemingway and Karchesy eds., Plenum Press, New York, pp. 503-515.
Czochanska et al., 1980, J.C.S. Perkin, 1:2278-86.
Lawrence J. Porter, "Flavans and Proanthocyanidins" in The Flavonoids, J. B. Harborne, ed., Chapman and Hall, New York, pp. 21-62.
J. W. T. Selway, "Antiviral Activity of Flavones and Flavans" in Plant Flavonoids in Biology and Medicine: Biochemical Pharmacological and Structure-Activity Relationship, Alan R. Liss, Inc., 1986, pp. 521-536.
Roux et al., Biochem. J. 82:320-324 (1962).
Konowalchuk et al., J. Food Science 41:1013-1017 (1976).
Konowalchuk et al., Appl. Environ. Microbiol., 32(6):757-763 (1976).
Konowalchuk et al., Appl. Environ. Microbiol. 36(6):798-801 (1978).
Konowalchuk et al., Appl. Environ. Microbiol. 35(6):1219-1220 (1978).
Takechi et al., Phytochem. 24(10):2245-2250 (1985).
Spencer et al., Phytochemistry 27(8):2397-2409 (1988).
Fukuchi et al., Antiviral Res. 11:285-298 (1989).
Scholz and Rimpler, Planta Medica 55:379 (1989).

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