Certain pyridyl methanones and pharmaceutical compositions conta

Details Certain pyridyl methanones and pharmaceutical compositions conta Certain pyridyl methanones and pharmaceutical compositions conta

1976-04-28

1978-02-28

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260297R, 260297B, 260297T, 2602948G, 2602948D, 260296M, 544 38, 544 39, C07D21350, A61K 3144

Patent

active

040768228

ABSTRACT:
New pyridine compounds of the general formula I ##STR1## wherein R denotes an optionally substituted cycloaliphatic hydrocarbon radical, Ph denotes an ortho-phenylene radical or especially a para-phenylene radical, A denotes a lower alkylene radical or a direct bond, X denotes an optionally functionally modified oxo group and Py denotes a pyridine radical, are useful as fibrinolytics, thrombolytics, antiphlogistics and as mild analgesics.

REFERENCES:
patent: 3262937 (1966-07-01), Pesson
patent: 3795677 (1974-03-01), Carr et al.
Berger et al., J. Am. Chem. Soc., vol. 72, pp. 1988-1990, (1950).
Hardtmann et al., J. Med. Chem., vol. 12, pp. 1093-1096, (1969).
Burger, Medicinal Chemistry, Second Edition, Interscience Pub., p. 497, 1960.

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