Pyrazolo [1,5-C]quinazoline derivatives and related compounds

Details Pyrazolo [1,5-C]quinazoline derivatives and related compounds Pyrazolo [1,5-C]quinazoline derivatives and related compounds

1976-07-02

1978-02-28

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602564F, A61K 31305, C07D48704

Patent

active

040768180

ABSTRACT:
Compounds are provided having the structure ##STR1## wherein R.sup.1 and R.sup.2 may be the same or different and R.sup.1 is hydrogen, alkyl of 1-3 carbons, phenyl optionally substituted by R.sup.4 or ##STR2## hydrogen, lower alkyl or phenyl optionally substituted by R.sup.4 with the proviso that at least one of R.sup.1 and R.sup.2 is ##STR3## R.sup.3 is hydrogen, lower alkyl, benzyl or phenyl optionally substituted by R.sup.4 ; and R.sup.4 and R.sup.5 are the same or different and represent hydrogen, lower alkyl, lower alkoxy, alkanoyloxy, benzyloxy, hydroxy, halogen (Cl, Br and F), nitro, and trifluoromethyl; R.sup.6 is hydrogen, lower alkyl, alkanoyl, aroyl, aralkanoyl, aralkyl or phenyl; and R.sup.7, R.sup.8, m and n are as defined hereinafter. These compounds are useful as anti-allergics.

REFERENCES:
patent: 3171740 (1965-03-01), Menzel et al.
patent: 3810894 (1974-05-01), Kranz et al.
patent: 3890324 (1975-06-01), Katner
patent: 3895027 (1975-07-01), Katner
patent: 3897434 (1975-07-01), Katner
patent: 3899508 (1975-08-01), Wikel
patent: 3903106 (1975-09-01), Katner
patent: 4002755 (1977-01-01), Yamamoto et al.

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