Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing
Patent
1988-08-23
1990-08-21
Robinson, Ellis P.
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
424117, 424119, 424122, A61K 912
Patent
active
049504770
ABSTRACT:
This invention concerns a method of preventing a pulmonary infection by a fungus in a subject susceptible to infection by the fungus comprising administering to the subject an amount per dose in an aerosol spray of a polyene or a pharmaceutically acceptable derivative thereof, effective to prevent pulmonary infection by the fungus. This invention further discloses a method of treating pulmonary aspergillosis in a subject comprising administering to the subject an amount per dose in an aerosol spray of a polyene, e.g., amphotericin B or pimaricin, or a pharmaceutically acceptable derivative thereof effective to treat aspergillosis.
REFERENCES:
Rodenhuis, S., et al. Invasive Pulmonary Aspergillosis in a Non-Immunosuppressed Patient: Successful Management with Systemic Amphotericin and Flucytosine and Inhaled Amphotericin. Thorax 1984; 39: 78-79.
Hargis, P. L., et al. Intracavitary Amphotericin B in the Treatment of Symptomatic Pulmonary Aspergillomas. Am. J. Med. 1980; 68: 389-394.
Swerdlow, B., Deresinsky, S. Development of Aspergillus Sinusitis in a Patient Receiving Amphotericin B. Am. J. Med. 1984; 76: 162-166.
Walzer, Y., Bear, R. a. Ureteral Obstruction of Renal Transplant Due to Ureteral Condidiasis. Urology 1983; 3: 295-297.
Ezdinli, E. Z., et al. Oral Amphotericin B for Candidiasis in Patients with Hematologic Neoplasms. JAMA 1979; 242: 258-260.
Christiansen, K. J., et al. Distribution and Activity of Amphotericin B in Humans. J. Infect. Dis. 1985; 152: 1037-1043.
McKendrick, D. W., Medlock, J. M. Pulmonary Moniliasis Treated with Nystatin Aerosol. Lancet 1958; 1: 621-622.
Gero, S., Szekely, J. Pulmonary Moniliasis Treated with Nystatin Aerosol. Lancet 1958; 2: 1229-1230.
Kohn, R., Hepler, R. Management of Limited Rhinoorbital Mucormycosis Without Exenteration. Opthalmology 1985; 92: 1440-1444.
Stenson, S., et al. Bilateral Endogenous Necrotizing Scleritis Due to Aspergillus Oryzae. Ann. Ophthalmology 1982; 14: 67-72.
Krakowa, P., et al. Local Treatment of Aspergilloma of the Lung With a Paste Containing Nystatin or Amphotericin B. Tubercle 1970; 51: 184-191.
Schubert, M. M., et al. Head and Neck Aspergilloisis in Patients Undergoing Bone Marrow Transplantation. Cancer 1986; 57: 1092-1096.
Meunier, F., et al. Prophylaxis of Aspergillosis in Neutropenic Cancer Patients with Nasal Spray of Amphotericin B: A Prospective Randomized Study. Program and abstracts of the 27th Interscience Conference on Antimicrobial Agents and Chemotherapy, New York, Oct. 4-7, 1987; Abstract No. 1346.
Domart, Y.; et al. Obstruction des voies urinaires par des bezoars candidosiques ou "fungus balls". Press Medicale 1986; 15: 153-156.
Polsky, B., et al. Intraventricular Therapy of Cryptococcal Meningitis via a Subcutaneous Resevior. Am. J. Med. 1986; 81: 24-28.
Kilburn, K. H. The Innocuousness and Possible Therapeutic Use of Aerosol Amphotericin B. Am. Rev. Resp. Dis. 1959; 80: 441-442.
Viera, D. F., et al. Invasive Pulmonary Aspergillosis After Near-Drowning. Intensive Care Med. 1984; 10: 203-204.
Ikemoto, H., et al. Pulmonary Aspergilloma; Sabouraudia 1971; 9: 30-35.
Schmitt, H. J., et al. MIC and Fungicidal Activity of Terbinafine Against Clinical Isolates of Aspergillus Spp. Antimicrobial Agents Chemotherapy 1988; in press.
Minsker O. B., et al. Treatment of Patients With Pulmonary Aspergillosis by Means of Inhalation of Amphotericin B Aerosols. Probl. Tuberk 1983; 4: 68-69.
Skobel, P., Fungal super Infections of Respitory Organs and Their Treatment by Inhalation and Instillation of Amphotericin B Anti-Infect and Instillation of Amphoterian B Anti-Infect and Moronal Pure Anti Infect Nystatin Anti Infect Human. Med. Welt 1966: 50: 2755-2759.
Boldrey, E. E. Bilateral Endogenous Aspergillus endophthalmitis. Retina 1981; 1: 171-174.
Staib, F., et al. Amphotericin B and Flucytosine Therapy of Aspergillus Pneumonia and Acute Renal Failure. Klin Wochenschr 1987; 65: 40-47.
Law, E. J., et al. Candida Parapsilosis Fungermia in Burn Patients: report of three cases. Burns Incl Therm Inj 1984; 10: 203-206.
Funada, H., et al. Total Intestinal Decontamination for Prevention of Infection in Bone Marrow Transplantation. Japanese Journal of Clinical Oncology 1983; 13 (Suppl 1): 111-126.
Rohatgi, P. K. Pulmonary Sporotrichosis. S Medical Journal 1980; 73: 1611-1617.
Shaikh, B. S. Colonization of Nasal Ulcers as a Source of Candida Parapsilosis. Arch Otolaryngol 1980; 106: 434-446.
Ward, P. H. c et al. Cocidioidomycosis of the Larynx in Infants and Adults, Ann Otol Rhino Laryngol 1977; 86: 655-660.
Armstrong Donald
Bernard Edward M.
Schmitt Heinz J.
Memorial Hospital For Cancer and Allied Dieseas
Prater P. L.
Robinson Ellis P.
White John P.
LandOfFree
Method of preventing and treating pulmonary infection by fungi u does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of preventing and treating pulmonary infection by fungi u, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of preventing and treating pulmonary infection by fungi u will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1676298