Pharmaceutical composition for relieving side effects of platinu

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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424649, 424545, 514492, A61K 3522, A61K 3324, A61K 3128

Patent

active

049504657

ABSTRACT:
A pharmaceutical composition for relieving side effects of platinum-containing drugs, containing an effective component of ulinastatin is provided. The platinum-containing drugs such as cisplatinum cause serious side effects including kidney dysfunction. The kidney dysfunction, particularly the one caused by a disorder or uriniferous tubule may be significantly relieved by administering the ulinastatin-containing agent of the present invention.

REFERENCES:
Chemical Abstracts 106:207421r (1987).
Chemical Abstracts 108:110567w (1988).
Chemical Abstracts, vol. 106, Abstract No. 169266j (1987), pp. 89-90.
Chemical Abstracts, vol. 108, Abstract No. 106109f (1988), p. 33.
Chemical Abstracts, vol. 108, Abstract No. 219525g (1988), p. 375.
Yamamura et al., "Clinical Evaluation of MR-20 for Various Shocks,"Progress in Medicine, vol. 129, pp. 730-738, 1984.
Honjo et al., "Clinical Effects of MR-20 for Various Pancreatitis,"Progress in Medicine, vol. 129, pp. 70-83, 1984; and
Proksch et al., "The Purification of the Trypsin Inhibitor From Human Pregnancy Urine,"Journal of Laboratory Clinical Medicine, vol. 79, pp. 491-499, 1972.

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