Substituted phenyl amidinoureas

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514464, 514465, 514596, 514597, 514598, 564 48, 564 49, 564 50, 564 51, 564 52, 564 53, 564 54, 549229, 549362, 549439, C07C12719, A61K 3117

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active

047044012

ABSTRACT:
This invention relates to a method of lowering blood pressure in humans and mammals using 2,6-disubstituted phenyl amidinoureas in which the phenyl ring is additionally substituted by a hydroxy, alkoxy, aralkoxy, alkenyloxy, alkynyloxy, haloacyloxy, or acyloxy group and to novel 2,6-disubstituted phenyl amidinoureas which possess pharmaceutical properties, including blood pressure lowering activity.

REFERENCES:
patent: 4060635 (1977-11-01), Diamond
patent: 4150154 (1979-04-01), Diamond
Douglas, Arzneim-Forsch-Drug Res., 28-2 (8A), 1435 (1978).

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