Epimerase

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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Details

435123, 435128, 435132, 435135, 435233, C12P 1926, C12P 1300, C12N 990

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active

059941057

ABSTRACT:
A novel polypeptide, acylglucosamine 2-epimerase as shown in FIG. 1 and derivatives thereof, DNA coding for said enzyme, a recombinant vector containing said enzyme, a transformant integrated thereinto said vector, a method for producing said enzyme and a method for producing N-acetylmannosamine and N-acetylneuraminic acid using renin binding protein.

REFERENCES:
patent: 5071750 (1991-12-01), Kragl et al.
Datta (1975) N-Acetylglucosamine 2-Epimerase from Hog Kidney, Methods in Enzymology 41 (Part B): 407-412, Jan. 1975.
Journal of Biological Chemistry, vol. 240, No. 4, 1965. MD US, pp. 1531-1536, XP002035865, Ghosh S et al: "The sialic acids".
Biochemistry, vol. 9, No. 17, 1970, Easton, PA US, pp. 3363-3370, XP002035866, DATTA ASIS: "Regulatory role of adenosine triphosphate on hog kidney N-acetyle-D-glucosamine 2-epimerase".
Journal of Biological Chemistry, vol. 266, No. 18, 1991, MD US, pp. 11896-11900, XP002035863, Inoue H et al "Leucine zipper motif in porcine renin-binding protein (RnBP) and its relationship to the formation of an RnBP-renin heterodimer and an RnBP homodimer".
Journal of Biological Chemistry, vol. 267, No. 18 1992, MD US, pp. 13007-13013, XP003035864, Takahashi S et al: The human gene for renin-binding protein.
J Biol Chem, Jul. 5, 1996, 271(27), P16294-9, United States, XP002035862, Maur I et al: "Molecular cloning and identification of N-acyl-D-glucosamine 2-epimerase from porcine kidney as a renin-binding protein".

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