Cosmetic skin preparation

Details Cosmetic skin preparation Cosmetic skin preparation

1998-01-16

1999-11-30

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

424401, 514861, 514886, 514887, 514937, A61K 900, A61K 600

Patent

active

059938307

ABSTRACT:
The present invention relates to a skin preparation comprising lipophilic and hydrophilic components, which is intended for application on skin. The skin preparation according to the present invention is characterized in that it exists as a two-phase system and it is capable of creating a semi-permeable membrane in the skin. The invention also relates to a process for the manufacture of the skin preparation as defined above, which is characterized in that the lipophilic components are dissolved in water in a separate container to be combined with hydrophilic components, which have been blended and brought to react in another vessel. Finally, the present invention also relates to different uses of the skin preparation as defined above.

REFERENCES:
Junginger. Structure studies of stearate creams. Pharm. Ind. 46 (7), 758-762, 1984.
STN International, file CAPLUS, CAPLUS accession No. 1985: 12187, H. Junginger: "Structure studies of stearate creams".
STN International, File CAPLUS, CAPLUS accession No. 1995: 1006804, Kao Corp: "Foam-forming skin cleaners containing higher fatty acid salts".
STN International, File CAPLUS, CAPLUS accession No. 1996: 750672, Schneider, Ina-Maria et al: "Evaluation of drug penetration into human skin ex vivo using branched fatty acids and propylene glycol".
STN International, File CAPLUS, CAPLUS accession No. 1992: 645569, Takeuchi, Yoshikasu et al: "Effects of fatty acids, fatty amines and propylene glycol on rat stratum corneum lipids and proteins in vitro measured by Fourier transfrom infrared/attenuated total reflection (FT-IR/ATR spectroscopy".
STN International, File CAPLUS, CAPLUS accession No. 1992: 537579, Komata, Tasuko et al: "In vitro percutaneous absorption of thiamine disulfide from a mixture of propylene glycol and fatty acid".
STN International, File CAPLUS, CAPLUS accession No. 1987: 561540, Kaiho, Fusao et al: Application of fatty alcohols to pharmaceutical dosage forms. Part IV. Percutaneous absorption of indomethacin from mixtures of fatty alcohol and propylene glycol (FAPG bases) through rat skin effect of fatty acid added to FAPG base.

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