Use of autoantibodies for tumor therapy and prophylaxis

Details Use of autoantibodies for tumor therapy and prophylaxis Use of autoantibodies for tumor therapy and prophylaxis

1998-07-14

1999-11-30

Budens, Robert D.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated to proteinaceous toxin or fragment thereof

4241331, 4241361, 4241381, 4241551, 4241781, 4241811, 5303871, 5303873, 53038815, 53038821, 5303888, 5303897, 5303911, 5303917, A61K 39395, C07K 1646

Patent

active

059938188

ABSTRACT:
A method of inhibiting the growth of a tumor cell in a mammal by administering to the mammal an autoantibody, e.g, an antinuclear autoantibody from an aged mammal, that binds to either one or both of a surface of a tumor cell and a protein released from a dead tumor cell. Also disclosed are natural and monoclonal antinuclear autoantibodies from aged mammals and a hybridoma cell line producing a monoclonal antinuclear autoantibody.

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