Method for the culture of the TRT/SHS virus, and vaccine therefr

Details Method for the culture of the TRT/SHS virus, and vaccine therefr Method for the culture of the TRT/SHS virus, and vaccine therefr

1987-08-17

1989-03-07

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

435235, 435236, 435237, A61K 3912, C12N 700

Patent

active

048104930

ABSTRACT:
The invention concerns a method for the culture of the infectious rhinotracheitis virus, TRT/SHS in the turkey that is also responsible for disorders in other bird species such as the infectious big head syndrome (or swollen head syndrome) in the chicken and guinea fowl.
According to the invention, samples are taken from sick animals that are inoculated on cell cultures consisting of a continuous line of monkey kidney cells.
A large quantity of the virus is obtained. This can be used as an antigen in the production of a vaccine that can be equally used for the immunization of all bird species.
The invention also applies to the production of vaccines from viral strains obtained by means of this method.

REFERENCES:
patent: 4505892 (1985-03-01), Apontoweil et al.
patent: 4692410 (1987-09-01), Apontoweil et al.

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