Method for enzyme immunoassay of pancreatic glucagon

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435188, 23230B, 424 8, 424 12, 2601125R, G01N 3354, C12N 996

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active

043129439

ABSTRACT:
A novel peptide-enzyme conjugate obtained by coupling a labeling enzyme with a peptide of the general formula:

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patent: 4220722 (1980-09-01), Rowley et al.
patent: 4221777 (1980-09-01), Nishino
Iwasa et al., "Enzyme Immunoassay of Pancreatic Glucagon at the Picogram Level Using B-D-Galactosudase as a Label", Chem. Abstracts, vol. 91, No. 25, (1979), p. 292, Abs. No. 206823h.
Schenck, "Production and Characterization of an Antiserum Against Pancreatic Glucagon", Clin. Chim. Acta., vol. 80, No. 3, (1977), pp. 455-463.
Ogawa et al., "Studies on Peptides, LXXVII, Synthesis of the Protected Heptadecapeptide Corresponding to Positions 13-29 of Avian Glucagon (Duck)," Chem. Abstracts, vol. 89, No. 21, (1978), p. 644, Abs. No. 180345k.
Imagawa et al., "Production of Anti-Glucagon Serums with a C-terminal Fragment of Pancreatic Glucagon", Chem. Abstracts, vol. 90, No. 23, (1979), p. 472, Abs. No. 184634x.
Ogawa et al., "Studies on Peptides LXXVII, Synthesis of the Protected Heptadecapeptide Corresponding to Positions 13-29 of Avian Glucagon (Duck)", Chem. Pharm. Bull., vol. 26, No. 5, (1978), pp. 1540-1548.
Wakimasu et al., "Synthesis of the Nonacosapeptide Corresponding to the Proposed Amino Acid Sequence of Turkey Glucagon", Chem. Absts., vol. 89, No. 21, (1978), p. 644, Abst. No. 180344j.
Iwasa et al., "Enzyme Immunoassay of Pancreatic Glucagon at the Picgram Level Using B-D-Galactosudase as a Label", J. Biochem., vol. 86, (1979), pp. 943-949.
Imagawa et al., "Production of Anti-Glucagon Sera with a C-Terminal Fragment of Pancreatic Glucagon", Endocrinol Japan, vol. 26, (1979), pp. 123-131.

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