Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1986-09-02
1987-07-07
Reamer, James H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514400, 514419, 514423, 514533, 514547, 548342, 548496, 548532, 548535, 560 16, 560 39, 560 40, 560153, 560169, 560170, 562426, 562444, 562445, 562557, 562559, 562564, 562567, A61K 31235, C07C10172
Patent
active
046788069
ABSTRACT:
Prodrugs of 3-hydroxy-3-methylglutarylcoenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formula (I): ##STR1## the amido ester moiety of which is in the L-configuration, and pharmaceutically acceptable salts thereof are disclosed.
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Baldwin John J.
Halczenko Wasyl
Hartman George
Pitzenberger Steven M.
DiPrima Joseph F.
Gray Bruce D.
Merck & Co. , Inc.
Reamer James H.
Sudol, Jr. Michael C.
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