Monoclonal antibodies for detection of an H (O) blood group anti

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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424 85, 435 68, 4351722, 435240, 435241, 435940, 436548, 530387, 935 95, 935110, 935 96, G01N 5300, C12N 1500

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active

046787470

ABSTRACT:
Monoclonal antibodies recognizing the difucosyl-type-2-H antigen on human cells and a method of producing said antibodies are disclosed. The monoclonal antibodies are useful in blood typing and in diagnosis of blood disorders and malignancies involving loss or gain of this H antigen.

REFERENCES:
patent: 4443427 (1984-04-01), Reinherz
Hybridoma-vol. 1, No. 2, (1982), pp. 169-225.
Anger et al.-Hybridoma-vol. 1, No. 2 (1982), pp. 139-147.
Knowles et al.-J. of Immunogenics vol. 9 (1982) pp. 69-76.

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