Propenoic acid derivatives diazole propenoic acid compounds whic

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514333, 514341, 514406, 514399, 514397, 546256, 546 14, 5462771, 546266, 546344, 546264, 546329, 546262, 5462754, 5462751, 5483111, 5483124, 5483381, 5483385, 5483641, 5483751, C07D40114, C07D23110, C07D23354, A61K 31415

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055412130

ABSTRACT:
A novel propenoic acid derivative which exhibits adenosine A1 antagonism is defined by the general formula (I): ##STR1## (wherein A represents an aromatic ring; R.sup.1 represents aryl or the like; R.sup.2, R.sup.3 and R.sup.4 each represent hydrogen, lower alkyl or the like; and R.sup.7 and R.sup.8 each represent lower alkyl or the like) or a pharmacologically acceptable salt thereof.

REFERENCES:
Chemical Abstracts, vol. 71, No. 13, Abstract 60.964t, Sep. 29, 1969, p. 402.
Chemical Abstracts, vol. 93, No. 7, Abstract 71,629t, Aug. 18, 1980, p. 965.
Chemical Abstracts, vol. 110, No. 25, Abstract 231, 632p, Jun. 19, 1989, p. 648.
Chemical Abstracts, vol. 111, No. 3, Abstract 23,508w, Jul. 17, 1989. pp. 617-618.

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