Methods for treatment of sepsis using branch chain amino acids

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514557, 514561, 514610, 514921, A61K 31415, A61K 3119, A61K 31195, A61K 3104

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active

053547713

ABSTRACT:
Methods for treatment of free-radical-mediated tissue injury, particularly sepsis, are provided wherein compositions containing at least one keto analog of a branched-chain amino acid are administered. The composition is administered orally or parenterally, preferably in frequent or continuous dosages. Preferred forms of the keto analogs are their ornithine, arginine, or sodium salts.

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