Substituted aliphatic amine-containing macrocyclic immunomodulat

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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540456, A61K 31395, C07D49118

Patent

active

055411894

ABSTRACT:
Compounds having the formula ##STR1## and the pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein one of R.sup.104 and R.sup.105 is hydrogen, and the other of R.sup.104 and R.sup.105 is a radical having the formula ##STR2## as well as pharmaceutically compositions containing such compounds and methods of immunomodulative therapy utilizing the same.

REFERENCES:
patent: 5189042 (1993-02-01), Goulet et al.
patent: 5208228 (1993-05-01), Ok et al.
patent: 5247076 (1993-09-01), Goulet et al.

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