Thiazolidine derivatives use

Details Thiazolidine derivatives use Thiazolidine derivatives use

1981-01-06

1983-03-15

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548183, C07D27704, A61K 31425

Patent

active

043767770

ABSTRACT:
A thiazolidine derivative of the formula: ##STR1## wherein R.sub.1 is hydrogen, hydroxyl, lower alkyl having 1 to 4 carbon atoms, lower alkoxy having 1 to 4 carbon atoms, or lower carboxylic acyloxy having 2 to 4 carbon atoms; each of R.sub.2 and R.sub.3 is hydroxyl, lower alkyl having 1 to 4 carbon atoms, lower alkoxy having 1 to 4 carbon atoms or lower carboxylic acyloxy having 2 to 4 carbon atoms or pharmaceutically acceptable salt thereof a is a novel compound having antiulcer activity and inhibitory effect on gastric acid secretion. The compound is useful as antiulcer agent or inhibitory agent of gastric acid secretion.

REFERENCES:
patent: 3200126 (1965-08-01), Satzinger
patent: 3311655 (1967-03-01), Boileau et al.
patent: 3825553 (1974-07-01), Diamond et al.
patent: 4287200 (1981-09-01), Kawamatsu et al.
Jour. of Medicinal Chemistry 13, 1009-1012, (1970).

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