Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-07-20
1983-03-15
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
546300, 546332, C07D21354, A61K 3144
Patent
active
043767753
ABSTRACT:
Disclosed and claimed are N-R-N-40 [4-(4-2-R.sub.2 -3-R.sub.3 -5-R.sub.5 -6-R.sub.6 -4-pyridinyl)phenyl]ureas (I) or pharmaceutically-acceptable acid-addition salts thereof, where R is hydrogen, methyl or ethyl, R.sub.2 is hydrogen, methyl, ethyl or hydroxyl, R.sub.6 hydrogen, methyl or ethyl, and R.sub.3 and R.sub.5 are each hydrogen or methyl, their cardiotonic use and their preparation.
REFERENCES:
patent: 3753993 (1973-08-01), Lesher et al.
patent: 3907808 (1975-09-01), Lesher et al.
patent: 4118557 (1978-10-01), Lesher
P. A. S. Smith, The Chemistry of Open-Chain Organic Nitrogen Compounds, vol. I, Benjamin Pub., p. 275, (1965).
Heilbron et al. [J. Chem. Soc. 1940, 1279].
Lesher George Y.
Page Donald F.
Bair Robert K.
Rotman Alan L.
Sterling Drug Inc.
Wyatt B. Woodrow
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