Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and ami

Details Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and ami Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and ami

1980-06-16

1982-03-23

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

548195, 424270, 546198, 546209, 42424851, 424267, C07D27720

Patent

active

043213723

ABSTRACT:
This invention encompasses orally effective antiulcer agents of the formula ##STR1## wherein X is hydroxy, (C.sub.1 -C.sub.5)-alkoxy, phenoxy, benzyloxy, or --NH(CH.sub.2).sub.n Y wherein n is an integer of value 2 to 4 and Y is di-(C.sub.1 -C.sub.3)-alkylamino, 1-pyrrolidinyl, 1-piperidinyl or 4-morpholinyl;

REFERENCES:
patent: 3966965 (1976-06-01), Sellstedt et al.
patent: 4150140 (1976-02-01), Hall et al.
patent: 4182766 (1980-01-01), Krasso
patent: 4183854 (1980-01-01), Crossley
patent: 4238496 (1980-12-01), Hess et al.
patent: 4246271 (1981-01-01), Cousse et al.
Sellstedt et al.; J. Med. Chem. 1869, pp. 926-933 (1975).

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