Isolated phenylalanine dehydrogenase gene and process for produc

Details Isolated phenylalanine dehydrogenase gene and process for produc Isolated phenylalanine dehydrogenase gene and process for produc

1990-05-10

1991-05-14

Teskin, Robin L.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

4352523, 43525233, 4353201, 536 27, C12N 902, C12N 102, C12N 1500, C07H 1512

Patent

active

050155822

ABSTRACT:
An isolated gene coding for phenylalanine dehydrogenase of a microorganism belonging to a genus selected from the group consisting of the genera Bacillus and Sporosarcina origin; plasmids containing the gene; microorganism transformed with the plasmid, a process for the production of phenylalanine dehydrogenase using the microorganism; and a process for the production of L-phenylalanine using the enzyme.

REFERENCES:
patent: 4590161 (1986-05-01), Kula et al.
Patent Abstracts of Japan, vol. 9, No. 138 (C-286) (1861), Jun. 13, 1985, JP 60-24192(A).
Ozaki et al., "Cloning and Nucleotide Sequencing of Phenylalanine Drhydrogenase Gene of Bacillus sphaericus", Gene, vol. 63, No. 2, pp. 337-341 (1988).
Asano et al., "Novel Phenylkalnine Dehydrogenases from Sporosarcina ureae and Bacillus sphaericus, " The Journal of Biological Chemistry, vol. 262, No. 21, pp. 10346-10354, Jul. 25, 1987.
Asano et al., "Phenylalanine Dehydrogenase of Bacillus badius, Purification, Characterization and Gene Cloning", Eur. J. Biochem., vol. 168, pp. 153-139, 1987.
Asano et al., "Bacillus Phenylalanine Dehydrogenase Produced in Escherichia coli, Its Purification and Application to L-Phenylalanine Synthesis," Agric. Biol. Chem., vol. 51, No. 9, pp. 2621-2623.

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