Pharmaceutically useful bis-basic ester and thioester derivative

Details Pharmaceutically useful bis-basic ester and thioester derivative Pharmaceutically useful bis-basic ester and thioester derivative

1973-06-15

1976-03-23

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424274, A61K 31235

Patent

active

039461122

ABSTRACT:
Bis-basic ester derivatives of the following general formula are useful in the treatment of conditions of delayed hypersensitivity. ##EQU1## wherein [W] represents an aromatic polycyclic nucleus selected from fluoranthene, fluorene, fluoren-9-ol, fluoren-9-one, carbazole, or N-(lower)alkyl carbazole; X represents oxygen or sulfur; A represents a straight or branched alkylene chain of from 2 to 6 carbon atoms; and each of R.sup.1 and R.sup.2 is hydrogen, straight or branched lower alkyl of from 1 to 4 carbon atoms, or alkenyl of from 3 to 6 carbon atoms having the vinyl unsaturation in other than the 1-position; and pharmaceutically useful acid addition salts thereof.

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