Electrochemical enzyme biosensor

Details Electrochemical enzyme biosensor Electrochemical enzyme biosensor

1995-11-20

1998-07-21

Bell, Bruce F.

Chemistry: electrical and wave energy

Apparatus

Electrolytic

204415, 4352871, 4352891, 435817, G01N 2726

Patent

active

057830568

ABSTRACT:
In the case of the electrochemical enzyme biosensor comprising noble metal electrodes, an electrochemical oxidation of pyridine nucleotides takes place, in particular of NADH. The noble metal electrodes have a microtexture rich in surface pores and having catalytic properties, as a result of which the overpotential required for electrochemical oxidation of the pyridine nucleotides is reduced. Owing to these microtextures, the surface area of an electrode is from 3 to 10 times larger than its geometric surface area.

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Wang et al, Anal. Chem. 1994, 66, 1007-1011 "Enzyme Microelectrode Array Strips for GLucose and Lactate", no month available.
Blaedel et al, Analytical Chemistry, vol. 47, No. 8, Jul. 1975 "Study of the Electrochemical Oxidation of Reduced Nicotinamide Adenine Dinucleotide".
Schmidt et al, Fresenius J. Anal. Chem. (1994) 349:607-612 "Application of Screen Printed Electrodes in Biochemical Analysis", no month available.
Gorton et al, Analytica Acta, 249 (1991) 43-54 "Amperometric Glucose Sensors Based on Immobilized Glucose-Oxidizing Enzymes and Chemically Modified Electrodes", no month available.
Gorton, L. J. Chem. Soc., Faraday Trans. I, 1986, 82, 1245-1258 "Chemically Modified Electrodes for the Electrocatalytic Oxidation of Nicotinamide Coenzymes", no month available.

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